Description
EDN (eosinophil-derived neurotoxin, eosinophil protein x, EPX), a cationic glycoprotein, which is released by activated eosinophiles, has strong cytotoxic characteristics and plays a significant role in the prevention of virus infections. It is released by the eosinophile granules in places where eosinophiles are mainly found: in the skin, lungs, urogenital and gastrointestinal tract, that is, in the organs acting as an entry point for pathogens. The accumulation of EDN in the intestine is associated with inflammation and tissue damage. In the case of Colitis ulcerosa and Crohn's disease, the EDN measurement enables the evaluation of a disease's activity and the prediction of a relapse